Karyopharm Therapeutics Inc

+0.16 (+14.54%)
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Market Cap (Intraday)146.74M
Current PEN/A
Forward PE N/A
2yr Forward PE N/A
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Estimates Current Quarter
Revenue$34.48 Million
Adjusted EPS-$0.33
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10-Day MA$1.26
50-Day MA$1.35
200-Day MA$1.20
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Karyopharm Therapeutics Inc Stock, NASDAQ:KPTI

85 Wells Avenue, Suite 210, 2nd floor, Newton, Massachusetts 02459-3298
United States of America
Phone: +1.617.658.0600
Number of Employees: 325


Karyopharm Therapeutics, Inc. is a commercial-stage pharmaceutical company, which engages in the discovery, development, and commercialization of drugs directed against nuclear export for the treatment of cancer and other diseases. Its Selective Inhibitor of Nuclear Export (SINE) compounds function by binding with and inhibiting the nuclear export protein XPO1 (or CRM1). Karyopharm�s compound, XPOVIO (selinexor), is approved in the U.S. in multiple hematologic malignancy indications, including in combination with Velcade (bortezomib) and dexamethasone for the treatment of adult patients with multiple myeloma after at least one prior therapy, in combination with dexamethasone for the treatment of adult patients with pretreated multiple myeloma and as a monotherapy for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma. In addition to single-agent and combination activity against a variety of human cancers, SINE compounds have also shown biological activity in models of neurodegeneration, inflammation, autoimmune disease, certain viruses, and wound-healing. Karyopharm has several investigational programs in clinical or preclinical development. The company was founded by Joseph Araujo, Ronald A. DePinho, Pamela A, Silver, Giulio Draetta, Michael G. Kauffman, and Sharon Shacham on December 22, 2008 and is headquartered in Newton, MA.